Nearly 107.000 people were deported from Westerbork on 97 transports. The first transport was to Auschwitz-Birkenau on 15th July, 1942. In 1943, from 2nd March to 16th November, there was a weekly rhythm; every Tuesday a train would depart with between one and three thousand people on board.
These deportations were organized from Berlin, stating the date, destination and number of deportees. The SS commander of Westerbork was responsible for preparing the transport. The decision of who should go was left to the Jewish leaders of the camp. The destination was usually Auschwitz or Sobibor. Occasionally the trains went to Bergen-Belsen and Theresienstadt and sometimes to other camps. 

The last major transport left on 13th September, 1944, with 279 Jews on board. Destined for Bergen-Belsen. Only 5.000 deportees survived the war.